pentobarbital will decrease the level or effect of lorlatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital and olopatadine intranasal each enhance sedation. Avoid or Use Alternate Drug. Coadministration will increase possibility of CNS despair, which can lead to additive impairment of psychomotor functionality and induce daytime impairment.
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pentobarbital will lower the level or result of naloxegol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Utilization of naloxegol with solid CYP3A4 inducers is not recommended
pentobarbital will lower the extent or impact of lefamulin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Stay away from coadministration of lefamulin with potent or moderate CYP3A inducers Unless of course the reward outweighs threats. Keep track of for diminished efficacy.
CONTRAINDICATIONS Barbiturates are contraindicated in patients with identified barbiturate sensitivity. Barbiturates may also be contraindicated in clients that has a record of manifest or latent porphyria.
pentobarbital will lessen the level or result of atorvastatin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
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pentobarbital will minimize the extent or influence of darunavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will minimize the level or influence get more info of conivaptan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will lessen the extent or result of fostemsavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.